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College of Pharmacy

PHAR 594 – Advances in Manipulating the Human Genome (3)

Covers current techniques in genetic engineering used to modify the characteristics of individuals as a prelude to possible future human genetic engineering, including advances in gene manipulation from early recombinant DNA techniques to CRISPR-Cas technology. Emphasizes manipulations of the genomes of individual mammals, and characterization of the effect of those manipulations at levels from the molecular to the physiological. Explores DNA/RNA/protein extraction, polymerase chain reaction, molecular cloning, sequencing (DNA, RNA, and chromatin), expression analyses, gene overexpression, silencing and perturbation. This course may be subject to Enforced Prerequisites that restrict registration into the course. Check the offerings below for more information.

For more information, contact OSU Ecampus at 800-667-1465 (option 1) or

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TermCRNSecCrP/NInstructorTypeStatusCapAvailWL CapWL Avail
Sp23570524003Kioussi, C.Online Open302400
Registration Restrictions
Recommended: Advanced Biochemistry or Cell and Molecular Biology
Level Limitations: +02 (Graduate)
Class Notes:

Textbooks  [ Textbooks]

Syllabus: Available in Canvas to students enrolled in this course. Or contact instructor to request syllabus. (Note: An ONID account is required to view OSU's online directory.)
Find textbooks for PHAR 594 at the OSU Beaver Store (current term only). For questions related to course materials, contact the OSU Beaver Store.

= Signifies the course as a Baccalaureate Core Course.
= Signifies that fees may apply to the course.
+ = Include restriction.
- = Exclude restriction.
* = Prereq may be taken prior to or simultaneously with this course.